ABSTRACT
Professor YANG Jun's clinical experience of acupuncture and moxibustion for oculomotor paralysis is summarized. Professor YANG Jun pays attention to disease differentiation and syndrome differentiation in the treatment of this disease. According to the characteristics of oculomotor paralysis, "early diagnosis and seeking treatment from the source" is advocated. According to the etiology and pathogenesis, professor YANG divides oculomotor paralysis into three types: the syndrome of wind-evil attacking collaterals, the syndrome of spleen-stomach weakness and the syndrome of qi-deficiency and blood-stasis. As such, the acupoints are selected according to syndrome differentiation, and several different acupuncture methods (pricking needling at eyelids, penetrating needling and lifting eyelids and contralateral- balance needling on the healthy side) are adopted to improve the symptoms of oculomotor paralysis. It is also suggested to use the combination of scalp acupuncture and electroacupuncture to achieve the best dose-effect state. Moreover, local stimulation around the eyes is important to achieve the effects of "qi reaching affected area".
Subject(s)
Humans , Acupuncture , Acupuncture Points , Acupuncture Therapy , Moxibustion , Ophthalmoplegia , SyndromeABSTRACT
Niemann-Pick disease, type C (NP-C), is caused by NPC1 or NPC2 gene mutations. Progressive neurological, psychiatric, and visceral symptoms are characteristic. Here, we present cases of a brother (Case 1) and sister (Case 2) in their mid-20s with gait disturbance and psychosis. For the Case 1, neurological examination revealed dystonia, ataxia, vertical supranuclear-gaze palsy (VSGP), and global cognitive impairment. Case 2 showed milder, but similar symptoms, with cortical atrophy. Abdominal computed tomography showed hepatosplenomegaly in both cases. NPC1 gene sequencing revealed compound heterozygote for exon 9 (c.1552C>T [R518W]) and exon 18 (c.2780C>T [A927V]). Filipin-staining tests were also positive. When a young patient with ataxia or dystonia shows VSGP, NP-C should be considered.
Subject(s)
Female , Humans , Male , Young Adult , Abdomen/diagnostic imaging , Asian People/genetics , Carrier Proteins/genetics , DNA Mutational Analysis , Exons , Gait Disorders, Neurologic/etiology , Membrane Glycoproteins/genetics , Niemann-Pick Disease, Type C/diagnosis , Psychotic Disorders/etiology , Republic of Korea , Siblings , Tomography, X-Ray ComputedABSTRACT
Las parálisis oculomotoras son una perdida total de la función de un músculo ocular. El objetivo del presente trabajo fue establecer la prevalencia de las parálisis oculomotoras en la consulta ortóptica, definir los signos y síntomas de las mismas y su etiología. Metodología: el estudio fue retrospectivo, se revisaron todas las historias clínicas de los pacientes remitidos a ortóptica atendidos en un consultorio particular, entre los años 2004 y 2006, seleccionando los casos de parálisis diagnosticadas, el análisis se realizó empleando el programa excel y se estableció la prevalencia de las parálisis oculomotoras según su etiología, signos y síntomas; así como también género, edad y asociación sistémica. Resultados. la población estudiada fue en total 3808 historias de las cuales, se obtuvo 30 casos positivos de parálisis oculomotoras lo cual representó el 0.78 por ciento de la muestra analizada.
Oculomotor paralysis is a total loss of the ocular musclefunction. The objective of this work was to establishthe prevalence of oculomotor paralysis in orthopticconsultation, to define the signs and symptoms as wellas their etiology. Methods: this was a retrospectivestudy. All the clinical records between 2004 and2006 whose patients were remitted to orthopticconsultation in a private doctors office were checked.Cases diagnosed with paralysis were chosen. Theanalysis was done through Excel and the prevalence ofoculomotor paralysis was established according to theiretiology, signs and symptoms. It also took into accountage, gender and systemic association. Results: a totalof 3808 clinical records were studied, out of which 30cases had oculomotor paralysis, which represented0.78 percent of the analyzed sample.
Subject(s)
Prevalence , Signs and SymptomsABSTRACT
bjective To induce a treatment program of evidence-based acupuncture and moxibustion for oculomotor paralysis by retrieving and analyzing the current literature for improving clinic technology.MethodsOne case was used as example and it was introduced how to raise clinical questions,retrieve relative literature,evaluate the retrieval literature and at last,stipulate treatment program based on the retrieval evidences.ResultsThe acupuncture and moxibustion treatment program for oculomotor paralysis established by evidence-based medicine was adopted to treat the patient for 10 times,as a result the patient got much better.Conclusion: Through clinically raising questions,searching for evidence,analyzing evidence,making a strategy decision,practicing evidence-based course,the patient could attain satisfactory therapeutic effect,and the physician could raise theoretical level and clinical ability.